The FLOW THROUGH design manifold effectively prevents contamination when several samples are injected in a common line of flow.

The figure on the left shows a conventional manifold, while the right shows the FLOW THROUGH design.

1. ① The buffer (blue area) flows in the common line from the left side port to the right side port in both of the manifold designs.
   
   

   

2. ② The sample is injected from the front side individual port to the common line, when one of the valves are open.
   
   

   

3. ③ In the conventional design, since the sample remains in the vertical flow path, CONTAMINATION occurs when the following sample enters the common line of flow.
   
   On the other hand, the FLOW THROUGH design does not have a vertical flow path; hence, NO CONTAMINATION.
   
   

   

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